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--- ohdsi-questions [2018/03/21 07:25]
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+++ ohdsi-questions [2018/04/13 23:45]
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   -Comparator Cohort - Patients treated with triptans for one year (short-term) and patients treated with triptans for more than one year (long-term).
   -Outcome - Sudden cardiac death, acute myocardial infarction, and stroke after exposure.
   -Risk Window - 1 day after treatment exposure starts to 0 days after treatment exposure ends.
+===Question - 9===
+To compare the risk of osteoporosis or fracture increase in postmenopausal hypothyroid patients using high strength levothyroxine versus patients using low strength levothyroxine.
+  -Treatment Cohort - On treatment postmenopausal (age >=50 years) patients with hypothyroidism exposed to high strength of levothyroxine (>=0.044 mg/day).
+  -Comparator Cohort - On treatment postmenopausal (age >=50 years) patients with hypothyroidism exposed to low strength of levothyroxine (< 0.044 mg/day).
+  -Outcome - Osteoporosis or Fracture.
+  -Risk Window: From the first day of treatment with high or low strength levothyroxine until the end of cohort study, end of follow-up or death.
 More discussion on these question can be seen here at [[http://forums.ohdsi.org/t/ohdsi-face-to-face-at-columbia-may2-3-community-study-a-thon/4008/10|OHDSI Forum]]

Shah Lab