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ohdsi-questions [2018/04/13 23:45]
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ohdsi-questions [2018/04/13 23:48]
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   -Outcome - Osteoporosis or Fracture.   -Outcome - Osteoporosis or Fracture.
   -Risk Window: From the first day of treatment with high or low strength levothyroxine until the end of cohort study, end of follow-up or death.   -Risk Window: From the first day of treatment with high or low strength levothyroxine until the end of cohort study, end of follow-up or death.
 +
 +===Question - 10===
 +To compare the risk of chronic kidney disease (CKD) among patients exposed to proton pump inhibitors versus patients not exposed to proton pump inhibitors.
 +  -Treatment Cohort - Patients with chronic exposure to proton pump inhibitors, age >= 18 years heaving no evidence of chronic kidney disease (eGFR < 60ml/min).
 +  -Comparator Cohort - Patients of age >= 18 with no exposure to proton pump inhibitors.
 +  -Outcome - Incidence of chronic kidney disease. 
 +
 +===Question - 11===
 +To compare the risk of Atherosclerotic Cardiovascular Disease (ACD) between patients with a diagnosis of hyperlipidemia (HLD) on statins and elevated triglycerides treated with fibrates versus patients with a diagnosis of HLD on statins and elevated triglycerides not treated with fibrates. 
 +  -Treatment Cohort - Patients with a diagnosis of HLD on statins and elevated triglycerides treated with fibrates.
 +  -Comparator cohort - Patients with a diagnosis of HLD on statins and elevated triglycerides not treated with fibrates.  
 +  -Outcome - Occurrence of Atherosclerotic Cardiovascular disease after treatment. 
 +  -Risk Window - 1 day after exposure start to 0 days after exposure ends.
 +
 +===Question - 12===
 +To compare the risk of Atherosclerotic Cardiovascular Disease (ACD) between patients with a diagnosis of hyperlipidemia (HLD) on statins with ideal cholesterol versus patients with a diagnosis of HLD on statins with elevated cholesterol. 
 +  -Treatment Cohort - Patients with the diagnosis of HLD treated with statins and have ideal cholesterol level.
 +  -Comparator Cohort - Patients with the diagnosis of HLD treated with statins and have elevated cholesterol level. 
 +  -Outcome - Risk of ACD.
 +  -Risk Window - 30 days after exposure to statins to 0 days after exposure. 
 +
  
    
  
 More discussion on these question can be seen here at [[http://forums.ohdsi.org/t/ohdsi-face-to-face-at-columbia-may2-3-community-study-a-thon/4008/10|OHDSI Forum]] More discussion on these question can be seen here at [[http://forums.ohdsi.org/t/ohdsi-face-to-face-at-columbia-may2-3-community-study-a-thon/4008/10|OHDSI Forum]]
ohdsi-questions.txt · Last modified: 2018/06/04 20:14 by nigam